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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINA1
All Species:
24.24
Human Site:
S405
Identified Species:
76.19
UniProt:
P01009
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01009
NP_000286.3
418
46737
S405
M
I
E
Q
N
T
K
S
P
L
F
M
G
K
V
Chimpanzee
Pan troglodytes
P61640
415
46307
S402
I
L
E
R
S
T
R
S
I
L
F
L
G
K
V
Rhesus Macaque
Macaca mulatta
XP_001099150
418
46681
S405
M
I
E
Q
N
T
K
S
P
L
F
M
G
K
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P22599
413
45956
S400
I
F
E
E
H
T
Q
S
P
I
F
V
G
K
V
Rat
Rattus norvegicus
P17475
411
46117
S399
I
V
E
S
E
T
Q
S
P
L
F
V
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518875
498
56680
S413
I
L
S
T
E
T
Q
S
L
L
F
L
G
K
V
Chicken
Gallus gallus
XP_421344
437
49694
S423
I
V
D
Q
Y
T
E
S
I
L
F
I
G
K
I
Frog
Xenopus laevis
NP_001081358
433
48891
H421
I
Y
D
M
E
T
K
H
T
L
F
L
G
R
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.1
91.6
N.A.
N.A.
64.3
68.6
N.A.
39.1
45.3
48.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.2
96.8
N.A.
N.A.
81.5
84.2
N.A.
54.8
65.2
64.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
N.A.
N.A.
53.3
60
N.A.
46.6
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
N.A.
N.A.
93.3
86.6
N.A.
73.3
86.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
63
13
38
0
13
0
0
0
0
0
0
0
0
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
100
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% G
% His:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
75
25
0
0
0
0
0
0
25
13
0
13
0
0
25
% I
% Lys:
0
0
0
0
0
0
38
0
0
0
0
0
0
88
0
% K
% Leu:
0
25
0
0
0
0
0
0
13
88
0
38
0
0
0
% L
% Met:
25
0
0
13
0
0
0
0
0
0
0
25
0
0
0
% M
% Asn:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% P
% Gln:
0
0
0
38
0
0
38
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
13
0
0
13
0
0
0
0
0
0
13
0
% R
% Ser:
0
0
13
13
13
0
0
88
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
13
0
100
0
0
13
0
0
0
0
0
0
% T
% Val:
0
25
0
0
0
0
0
0
0
0
0
25
0
0
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _